Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

Intestinal epithelial barrier properties are maintained by a junctional complex consisting of tight junctions (TJ), adherens junctions (AJ) and desmosomes. Desmoglein 2 (Dsg2), an adhesion molecule of desmosomes and the only Dsg isoform expressed in enterocytes, is required for epithelial barrier pr...

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Detalles Bibliográficos
Autores principales: Ungewiß, Hanna, Vielmuth, Franziska, Suzuki, Shintaro T., Maiser, Andreas, Harz, Hartmann, Leonhardt, Heinrich, Kugelmann, Daniela, Schlegel, Nicolas, Waschke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524837/
https://www.ncbi.nlm.nih.gov/pubmed/28740231
http://dx.doi.org/10.1038/s41598-017-06713-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524837/
https://www.ncbi.nlm.nih.gov/pubmed/28740231
http://dx.doi.org/10.1038/s41598-017-06713-y

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