p38 MAPK signaling and phosphorylations in the BRCT1 domain regulate XRCC1 recruitment to sites of DNA damage

XRCC1 is a scaffold protein involved in base excision repair and single strand break repair. It is a phosphoprotein that contains more than 45 phosphorylation sites, however only a few of these have been characterized and connected to specific kinases and functions. Mitogen activated protein kinases...

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Detalles Bibliográficos
Autores principales: de Sousa, Mirta Mittelstedt Leal, Bjørås, Karine Øian, Hanssen-Bauer, Audun, Solvang-Garten, Karin, Otterlei, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524842/
https://www.ncbi.nlm.nih.gov/pubmed/28740101
http://dx.doi.org/10.1038/s41598-017-06770-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524842/
https://www.ncbi.nlm.nih.gov/pubmed/28740101
http://dx.doi.org/10.1038/s41598-017-06770-3

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