Mechanisms and Specificity of Phenazine Biosynthesis Protein PhzF

Phenazines are bacterial virulence and survival factors with important roles in infectious disease. PhzF catalyzes a key reaction in their biosynthesis by isomerizing (2 S,3 S)-2,3-dihydro-3-hydroxy anthranilate (DHHA) in two steps, a [1,5]-hydrogen shift followed by tautomerization to an aminoketon...

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Detalles Bibliográficos
Autores principales: Diederich, Christina, Leypold, Mario, Culka, Martin, Weber, Hansjörg, Breinbauer, Rolf, Ullmann, G. Matthias, Blankenfeldt, Wulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524880/
https://www.ncbi.nlm.nih.gov/pubmed/28740244
http://dx.doi.org/10.1038/s41598-017-06278-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524880/
https://www.ncbi.nlm.nih.gov/pubmed/28740244
http://dx.doi.org/10.1038/s41598-017-06278-w

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