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Mechanically stable fibrin scaffolds promote viability and induce neurite outgrowth in neural aggregates derived from human induced pluripotent stem cells

Recent work demonstrated that 3D fibrin scaffolds function as an effective substrate for engineering tissues from pluripotent stem cells. However, the rapid degradation rate of fibrin remains a major limitation when differentiating human pluripotent stem cells for tissue engineering applications. Th...

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Detalles Bibliográficos
Autores principales: Robinson, Meghan, Douglas, Sarah, Michelle Willerth, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524903/
https://www.ncbi.nlm.nih.gov/pubmed/28740258
http://dx.doi.org/10.1038/s41598-017-06570-9