CDKL5 localizes at the centrosome and midbody and is required for faithful cell division

The cyclin-dependent kinase-like 5 (CDKL5) gene has been associated with rare neurodevelopmental disorders characterized by the early onset of seizures and intellectual disability. The CDKL5 protein is widely expressed in most tissues and cells with both nuclear and cytoplasmic localization. In post...

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Detalles Bibliográficos
Autores principales: Barbiero, Isabella, Valente, Davide, Chandola, Chetan, Magi, Fiorenza, Bergo, Anna, Monteonofrio, Laura, Tramarin, Marco, Fazzari, Maria, Soddu, Silvia, Landsberger, Nicoletta, Rinaldo, Cinzia, Kilstrup-Nielsen, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524905/
https://www.ncbi.nlm.nih.gov/pubmed/28740074
http://dx.doi.org/10.1038/s41598-017-05875-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524905/
https://www.ncbi.nlm.nih.gov/pubmed/28740074
http://dx.doi.org/10.1038/s41598-017-05875-z

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