Overexpression of DNMT3b target genes during Enteric Nervous System development contribute to the onset of Hirschsprung disease

Hirschsprung disease (HSCR) is attributed to a failure of neural crest cells (NCCs) to migrate, proliferate, differentiate and/or survive in the bowel wall during embryonic Enteric Nervous System (ENS) development. ENS formation is the result from a specific gene expression pattern regulated by epig...

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Detalles Bibliográficos
Autores principales: Villalba-Benito, Leticia, Torroglosa, Ana, Fernández, Raquel María, Ruíz-Ferrer, Macarena, Moya-Jiménez, María José, Antiñolo, Guillermo, Borrego, Salud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524929/
https://www.ncbi.nlm.nih.gov/pubmed/28740121
http://dx.doi.org/10.1038/s41598-017-06539-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524929/
https://www.ncbi.nlm.nih.gov/pubmed/28740121
http://dx.doi.org/10.1038/s41598-017-06539-8

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