The Role of Inflammation in β-cell Dedifferentiation

Chronic inflammation impairs insulin secretion and sensitivity. β-cell dedifferentiation has recently been proposed as a mechanism underlying β-cell failure in T2D. Yet the effect of inflammation on β-cell identity in T2D has not been studied. Therefore, we investigated whether pro-inflammatory cyto...

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Detalles Bibliográficos
Autores principales: Nordmann, Thierry M., Dror, Erez, Schulze, Friederike, Traub, Shuyang, Berishvili, Ekaterine, Barbieux, Charlotte, Böni-Schnetzler, Marianne, Donath, Marc Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524956/
https://www.ncbi.nlm.nih.gov/pubmed/28740254
http://dx.doi.org/10.1038/s41598-017-06731-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524956/
https://www.ncbi.nlm.nih.gov/pubmed/28740254
http://dx.doi.org/10.1038/s41598-017-06731-w

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