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The Role of Inflammation in β-cell Dedifferentiation
Chronic inflammation impairs insulin secretion and sensitivity. β-cell dedifferentiation has recently been proposed as a mechanism underlying β-cell failure in T2D. Yet the effect of inflammation on β-cell identity in T2D has not been studied. Therefore, we investigated whether pro-inflammatory cyto...
Autores principales: | Nordmann, Thierry M., Dror, Erez, Schulze, Friederike, Traub, Shuyang, Berishvili, Ekaterine, Barbieux, Charlotte, Böni-Schnetzler, Marianne, Donath, Marc Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524956/ https://www.ncbi.nlm.nih.gov/pubmed/28740254 http://dx.doi.org/10.1038/s41598-017-06731-w |
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