Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress

Alantolactone (ALT), a sesquiterpene lactone component of Inula helenium, has been reported to exert anticancer activity in various cancers. However, the cellular targets and underlying mechanism of anticancer activity of ALT in various cancers including lung cancer has not been fully defined. In th...

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Detalles Bibliográficos
Autores principales: Maryam, Amara, Mehmood, Tahir, Zhang, He, Li, Yongming, Khan, Muhammad, Ma, Tonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524969/
https://www.ncbi.nlm.nih.gov/pubmed/28740138
http://dx.doi.org/10.1038/s41598-017-06535-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524969/
https://www.ncbi.nlm.nih.gov/pubmed/28740138
http://dx.doi.org/10.1038/s41598-017-06535-y

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