A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance

Copper resistance is a key virulence trait of the uropathogen Proteus mirabilis. Here we show that P. mirabilis ScsC (PmScsC) contributes to this defence mechanism by enabling swarming in the presence of copper. We also demonstrate that PmScsC is a thioredoxin-like disulfide isomerase but, unlike ot...

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Detalles Bibliográficos
Autores principales: Furlong, Emily J., Lo, Alvin W., Kurth, Fabian, Premkumar, Lakshmanane, Totsika, Makrina, Achard, Maud E. S., Halili, Maria A., Heras, Begoña, Whitten, Andrew E., Choudhury, Hassanul G., Schembri, Mark A., Martin, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524982/
https://www.ncbi.nlm.nih.gov/pubmed/28722010
http://dx.doi.org/10.1038/ncomms16065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524982/
https://www.ncbi.nlm.nih.gov/pubmed/28722010
http://dx.doi.org/10.1038/ncomms16065

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