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A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance
Copper resistance is a key virulence trait of the uropathogen Proteus mirabilis. Here we show that P. mirabilis ScsC (PmScsC) contributes to this defence mechanism by enabling swarming in the presence of copper. We also demonstrate that PmScsC is a thioredoxin-like disulfide isomerase but, unlike ot...
Autores principales: | Furlong, Emily J., Lo, Alvin W., Kurth, Fabian, Premkumar, Lakshmanane, Totsika, Makrina, Achard, Maud E. S., Halili, Maria A., Heras, Begoña, Whitten, Andrew E., Choudhury, Hassanul G., Schembri, Mark A., Martin, Jennifer L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524982/ https://www.ncbi.nlm.nih.gov/pubmed/28722010 http://dx.doi.org/10.1038/ncomms16065 |
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