Noncoding Centromeric RNA Expression Impairs Chromosome Stability in Human and Murine Stem Cells

We analyzed the effect of transcribed noncoding RNA centromeric satellites on chromosome segregation in normal human and murine stem and fibrosarcoma cells. The overexpression of different centromeric alphoid DNAs in all cell lines induced a marked increase in chromosome mis-segregation in anaphase....

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Detalles Bibliográficos
Autores principales: Chan, David Y. L., Moralli, Daniela, Khoja, Suhail, Monaco, Zoia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525099/
https://www.ncbi.nlm.nih.gov/pubmed/28781416
http://dx.doi.org/10.1155/2017/7506976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525099/
https://www.ncbi.nlm.nih.gov/pubmed/28781416
http://dx.doi.org/10.1155/2017/7506976

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