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Cu-Mediated C–H (18)F-Fluorination of Electron-Rich (Hetero)arenes

[Image: see text] This communication describes a method for the nucleophilic radiofluorination of electron-rich arenes. The reaction involves the initial C(sp(2))–H functionalization of an electron-rich arene with MesI(OH)OTs to form a (mesityl)(aryl)iodonium salt. This salt is then used in situ in...

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Detalles Bibliográficos
Autores principales: McCammant, Matthew S., Thompson, Stephen, Brooks, Allen F., Krska, Shane W., Scott, Peter J. H., Sanford, Melanie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525103/
https://www.ncbi.nlm.nih.gov/pubmed/28665619
http://dx.doi.org/10.1021/acs.orglett.7b01902