Germline EMSY sequence alterations in hereditary breast cancer and ovarian cancer families

BACKGROUND: BRCA1 and BRCA2 mutations explain approximately one-fifth of the inherited susceptibility in high-risk Finnish hereditary breast and ovarian cancer (HBOC) families. EMSY is located in the breast cancer-associated chromosomal region 11q13. The EMSY gene encodes a BRCA2-interacting protein...

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Detalles Bibliográficos
Autores principales: Määttä, Kirsi M., Nurminen, Riikka, Kankuri-Tammilehto, Minna, Kallioniemi, Anne, Laasanen, Satu-Leena, Schleutker, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525221/
https://www.ncbi.nlm.nih.gov/pubmed/28738860
http://dx.doi.org/10.1186/s12885-017-3488-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525221/
https://www.ncbi.nlm.nih.gov/pubmed/28738860
http://dx.doi.org/10.1186/s12885-017-3488-x

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