High levels of circulating folate concentrations are associated with DNA methylation of tumor suppressor and repair genes p16, MLH1, and MGMT in elderly Chileans

BACKGROUND: Changes in DNA methylation, one of the most studied epigenetic mechanisms, are considered an initial marker for early cancer detection. We evaluated how availability of dietary factors (folates and vitamin B12) involved in one-carbon metabolism may contribute to DNA methylation changes o...

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Detalles Bibliográficos
Autores principales: Sanchez, Hugo, Hossain, Mohammad B., Lera, Lydia, Hirsch, Sandra, Albala, Cecilia, Uauy, Ricardo, Broberg, Karin, Ronco, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525256/
https://www.ncbi.nlm.nih.gov/pubmed/28748002
http://dx.doi.org/10.1186/s13148-017-0374-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525256/
https://www.ncbi.nlm.nih.gov/pubmed/28748002
http://dx.doi.org/10.1186/s13148-017-0374-y

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