MATCHER: manifold alignment reveals correspondence between single cell transcriptome and epigenome dynamics

Single cell experimental techniques reveal transcriptomic and epigenetic heterogeneity among cells, but how these are related is unclear. We present MATCHER, an approach for integrating multiple types of single cell measurements. MATCHER uses manifold alignment to infer single cell multi-omic profil...

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Detalles Bibliográficos
Autores principales: Welch, Joshua D., Hartemink, Alexander J., Prins, Jan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525279/
https://www.ncbi.nlm.nih.gov/pubmed/28738873
http://dx.doi.org/10.1186/s13059-017-1269-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525279/
https://www.ncbi.nlm.nih.gov/pubmed/28738873
http://dx.doi.org/10.1186/s13059-017-1269-0

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