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Unexpected complexity in the interference activity of a cloned influenza defective interfering RNA
BACKGROUND: Defective interfering (DI) viruses are natural antivirals made by nearly all viruses. They have a highly deleted genome (thus being non-infectious) and interfere with the replication of genetically related infectious viruses. We have produced the first potential therapeutic DI virus for...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525295/ https://www.ncbi.nlm.nih.gov/pubmed/28738877 http://dx.doi.org/10.1186/s12985-017-0805-6 |