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Characterization of axonal transport defects in Drosophila Huntingtin mutants
Polyglutamine (polyQ) expansion within Huntingtin (Htt) causes the fatal neurodegenerative disorder Huntington’s Disease (HD). Although Htt is ubiquitously expressed and conserved from Drosophila to humans, its normal biological function is still being elucidated. Here we characterize a role for the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525331/ https://www.ncbi.nlm.nih.gov/pubmed/27309588 http://dx.doi.org/10.1080/01677063.2016.1202950 |