miRNA-34c-5p inhibits amphiregulin-induced ovarian cancer stemness and drug resistance via downregulation of the AREG-EGFR-ERK pathway

Epithelial ovarian cancer is the most lethal gynecological cancer mainly due to late diagnosis, easy spreading and rapid development of chemoresistance. Cancer stem cells are considered to be one of the main mechanisms for chemoresistance, as well as metastasis and recurrent disease. To explore the...

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Detalles Bibliográficos
Autores principales: Tung, S-L, Huang, W-C, Hsu, F-C, Yang, Z-P, Jang, T-H, Chang, J-W, Chuang, C-M, Lai, C-R, Wang, L-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525454/
https://www.ncbi.nlm.nih.gov/pubmed/28459431
http://dx.doi.org/10.1038/oncsis.2017.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525454/
https://www.ncbi.nlm.nih.gov/pubmed/28459431
http://dx.doi.org/10.1038/oncsis.2017.25

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