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Structural Basis for Selectivity and Diversity in Angiotensin II Receptors

Angiotensin II receptors, AT(1)R and AT(2)R, serve as key components of the renin-angiotensin-aldosterone system. While AT(1)R plays a central role in the regulation of blood pressure, the function of AT(2)R is enigmatic with a variety of reported effects. To elucidate the mechanisms for the functio...

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Detalles Bibliográficos
Autores principales: Zhang, Haitao, Han, Gye Won, Batyuk, Alexander, Ishchenko, Andrii, White, Kate L., Patel, Nilkanth, Sadybekov, Anastasiia, Zamlynny, Beata, Rudd, Michael T., Hollenstein, Kaspar, Tolstikova, Alexandra, White, Thomas A., Hunter, Mark S., Weierstall, Uwe, Liu, Wei, Babaoglu, Kerim, Moore, Eric L., Katz, Ryan D., Shipman, Jennifer M., Garcia-Calvo, Margarita, Sharma, Sujata, Sheth, Payal, Soisson, Stephen M., Stevens, Raymond C., Katritch, Vsevolod, Cherezov, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525545/
https://www.ncbi.nlm.nih.gov/pubmed/28379944
http://dx.doi.org/10.1038/nature22035