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Structural Basis for Selectivity and Diversity in Angiotensin II Receptors
Angiotensin II receptors, AT(1)R and AT(2)R, serve as key components of the renin-angiotensin-aldosterone system. While AT(1)R plays a central role in the regulation of blood pressure, the function of AT(2)R is enigmatic with a variety of reported effects. To elucidate the mechanisms for the functio...
Autores principales: | Zhang, Haitao, Han, Gye Won, Batyuk, Alexander, Ishchenko, Andrii, White, Kate L., Patel, Nilkanth, Sadybekov, Anastasiia, Zamlynny, Beata, Rudd, Michael T., Hollenstein, Kaspar, Tolstikova, Alexandra, White, Thomas A., Hunter, Mark S., Weierstall, Uwe, Liu, Wei, Babaoglu, Kerim, Moore, Eric L., Katz, Ryan D., Shipman, Jennifer M., Garcia-Calvo, Margarita, Sharma, Sujata, Sheth, Payal, Soisson, Stephen M., Stevens, Raymond C., Katritch, Vsevolod, Cherezov, Vadim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525545/ https://www.ncbi.nlm.nih.gov/pubmed/28379944 http://dx.doi.org/10.1038/nature22035 |
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