A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model Using Three Targeted Drugs

PURPOSE: To compare the efficacy of microneedle-delivered suprachoroidal (SC) pazopanib to intravitreal (Ivit) delivery of pazopanib, bevacizumab, or a fusion protein hI-con1 versus vehicle controls on choroidal neovascularization (CNV) growth in a pig model. METHODS: Forty-one pigs were injected on...

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Detalles Bibliográficos
Autores principales: Tran, Jeffrey, Craven, Caroline, Wabner, Kathy, Schmit, Jenn, Matter, Brock, Kompella, Uday, Grossniklaus, Hans E., Olsen, Timothy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525553/
https://www.ncbi.nlm.nih.gov/pubmed/28738417
http://dx.doi.org/10.1167/iovs.16-21230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525553/
https://www.ncbi.nlm.nih.gov/pubmed/28738417
http://dx.doi.org/10.1167/iovs.16-21230

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