Conditionally Immortal Slc4a11(−/−) Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11(−/−) Mouse Model

PURPOSE: To establish conditionally immortal mouse corneal endothelial cell lines with genetically matched Slc4a11(+/+) and Slc4a11(−/−) mice as a model for investigating pathology and therapies for SLC4A11 associated congenital hereditary endothelial dystrophy (CHED) and Fuchs' endothelial cor...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Wenlin, Ogando, Diego G., Kim, Edward T., Choi, Moon-Jung, Li, Hongde, Tenessen, Jason M., Bonanno, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525555/
https://www.ncbi.nlm.nih.gov/pubmed/28738416
http://dx.doi.org/10.1167/iovs.17-21781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525555/
https://www.ncbi.nlm.nih.gov/pubmed/28738416
http://dx.doi.org/10.1167/iovs.17-21781

Ejemplares similares