Cargando…
Conditionally Immortal Slc4a11(−/−) Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11(−/−) Mouse Model
PURPOSE: To establish conditionally immortal mouse corneal endothelial cell lines with genetically matched Slc4a11(+/+) and Slc4a11(−/−) mice as a model for investigating pathology and therapies for SLC4A11 associated congenital hereditary endothelial dystrophy (CHED) and Fuchs' endothelial cor...
Autores principales: | Zhang, Wenlin, Ogando, Diego G., Kim, Edward T., Choi, Moon-Jung, Li, Hongde, Tenessen, Jason M., Bonanno, Joseph A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525555/ https://www.ncbi.nlm.nih.gov/pubmed/28738416 http://dx.doi.org/10.1167/iovs.17-21781 |
Ejemplares similares
-
Inducible Slc4a11 Knockout Triggers Corneal Edema Through Perturbation of Corneal Endothelial Pump
por: Ogando, Diego G., et al.
Publicado: (2021) -
Energy Shortage in Human and Mouse Models of SLC4A11-Associated Corneal Endothelial Dystrophies
por: Zhang, Wenlin, et al.
Publicado: (2020) -
Mitochondrial Targeting of the Ammonia-Sensitive Uncoupler SLC4A11 by the Chaperone-Mediated Carrier Pathway in Corneal Endothelium
por: Choi, Moonjung, et al.
Publicado: (2021) -
Corneal Endothelial Pump Coupling to Lactic Acid Efflux in the Rabbit and Mouse
por: Li, Shimin, et al.
Publicado: (2020) -
Mitochondrial ROS in Slc4a11 KO Corneal Endothelial Cells Lead to ER Stress
por: Shyam, Rajalekshmy, et al.
Publicado: (2022)