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[(177)Lu]pentixather: Comprehensive Preclinical Characterization of a First CXCR4-directed Endoradiotherapeutic Agent

Purpose: Based on the clinical relevance of the chemokine receptor 4 (CXCR4) as a molecular target in cancer and on the success of [(68)Ga]pentixafor as an imaging probe for high-contrast visualization of CXCR4-expression, the spectrum of clinical CXCR4-targeting was expanded towards peptide recepto...

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Detalles Bibliográficos
Autores principales: Schottelius, Margret, Osl, Theresa, Poschenrieder, Andreas, Hoffmann, Frauke, Beykan, Seval, Hänscheid, Heribert, Schirbel, Andreas, Buck, Andreas K., Kropf, Saskia, Schwaiger, Markus, Keller, Ulrich, Lassmann, Michael, Wester, Hans-Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525741/
https://www.ncbi.nlm.nih.gov/pubmed/28744319
http://dx.doi.org/10.7150/thno.19119