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PSMA-Targeted Theranostic Nanocarrier for Prostate Cancer

Herein, we report the use of a theranostic nanocarrier (Folate-HBPE(CT20p)) to deliver a therapeutic peptide to prostate cancer tumors that express PSMA (folate hydrolase 1). The therapeutic peptide (CT20p) targets and inhibits the chaperonin-containing TCP-1 (CCT) protein-folding complex, is select...

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Detalles Bibliográficos
Autores principales: Flores, Orielyz, Santra, Santimukul, Kaittanis, Charalambos, Bassiouni, Rania, Khaled, Amr S, Khaled, Annette R., Grimm, Jan, Perez, J Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525751/
https://www.ncbi.nlm.nih.gov/pubmed/28744329
http://dx.doi.org/10.7150/thno.18879