Cargando…

Role of mammalian target of rapamycin signaling in autophagy and the neurodegenerative process using a senescence accelerated mouse-prone 8 model

The mammalian target of rapamycin (mTOR) kinase is an inhibitor of autophagy, which is an intracellular system involved in the degradation of long-lived proteins and organelles in lysosomes. Recent evidence suggests that the steady incline in mTOR function during aging may be associated with the cog...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yanyong, Ma, Qinying, Ma, Xiaowei, Zhang, Zhongxia, Liu, Na, Wang, Mingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526151/
https://www.ncbi.nlm.nih.gov/pubmed/28810557
http://dx.doi.org/10.3892/etm.2017.4618