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Sivelestat sodium hydrate improves post-traumatic knee osteoarthritis through nuclear factor-κB in a rat model

As a specific inhibitor of neutrophil elastase, sivelestat sodium hydrate has primarily been used in the treatment of acute lung injury caused by various factors since its approval in 2002. Sivelestat sodium hydrate also improves post-traumatic knee osteoarthritis (KOA), although its underlying mech...

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Detalles Bibliográficos
Autores principales: Yu, Xiaofeng, Zhao, Lijun, Yu, Zhiping, Yu, Changzheng, Bi, Jianfei, Sun, Binglong, Cong, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526152/
https://www.ncbi.nlm.nih.gov/pubmed/28810618
http://dx.doi.org/10.3892/etm.2017.4684