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An entry-competent intermediate state of the HIV-1 envelope glycoproteins

The human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins (Env) mediate viral entry and are the sole target of neutralizing antibodies. Recent studies show that the metastable HIV-1 Env trimer can transit among three conformational states: State 1, State 3, and State 2, corresponding to...

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Detalles Bibliográficos
Autores principales: Herschhorn, Alon, Sodroski, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526225/
https://www.ncbi.nlm.nih.gov/pubmed/28752105
http://dx.doi.org/10.14800/rci.1544