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An entry-competent intermediate state of the HIV-1 envelope glycoproteins
The human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins (Env) mediate viral entry and are the sole target of neutralizing antibodies. Recent studies show that the metastable HIV-1 Env trimer can transit among three conformational states: State 1, State 3, and State 2, corresponding to...
Autores principales: | Herschhorn, Alon, Sodroski, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526225/ https://www.ncbi.nlm.nih.gov/pubmed/28752105 http://dx.doi.org/10.14800/rci.1544 |
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