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Suppressing miR-199a-3p by promoter methylation contributes to tumor aggressiveness and cisplatin resistance of ovarian cancer through promoting DDR1 expression

BACKGROUND: Discoidin Domain Receptor 1 (DDR1) belongs to the family of collagen receptor tyrosine kinases that confers the progression of various cancers. Aberrant expression of DDR1 was detected in several human cancers including ovarian cancer, which had been shown to increase the migration and i...

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Detalles Bibliográficos
Autores principales: Deng, Yuao, Zhao, Fang, Hui, Liu, Li, Xiuyun, Zhang, Danyu, Lin, Wang, Chen, Zhiqiang, Ning, Yingxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526233/
https://www.ncbi.nlm.nih.gov/pubmed/28743276
http://dx.doi.org/10.1186/s13048-017-0333-4