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Suppressing miR-199a-3p by promoter methylation contributes to tumor aggressiveness and cisplatin resistance of ovarian cancer through promoting DDR1 expression
BACKGROUND: Discoidin Domain Receptor 1 (DDR1) belongs to the family of collagen receptor tyrosine kinases that confers the progression of various cancers. Aberrant expression of DDR1 was detected in several human cancers including ovarian cancer, which had been shown to increase the migration and i...
Autores principales: | Deng, Yuao, Zhao, Fang, Hui, Liu, Li, Xiuyun, Zhang, Danyu, Lin, Wang, Chen, Zhiqiang, Ning, Yingxia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526233/ https://www.ncbi.nlm.nih.gov/pubmed/28743276 http://dx.doi.org/10.1186/s13048-017-0333-4 |
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