Inhibition of T cell-mediated inflammation in uveitis by a novel anti-CD3 antibody

BACKGROUND: A novel anti-mouse CD3ε antibody, Dow2, recognizes mouse CD3ε without activating T cells and suppresses T-cell activation. The purpose of this study was to determine whether Dow2 can inhibit T cells in uveitis. METHODS: Experimental autoimmune uveitis (EAU) was induced in mice by immuniz...

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Detalles Bibliográficos
Autores principales: Sugita, Sunao, Shimizu, Jun, Makabe, Kenichi, Keino, Hiroshi, Watanabe, Takeshi, Takahashi, Masayo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526238/
https://www.ncbi.nlm.nih.gov/pubmed/28743289
http://dx.doi.org/10.1186/s13075-017-1379-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526238/
https://www.ncbi.nlm.nih.gov/pubmed/28743289
http://dx.doi.org/10.1186/s13075-017-1379-9

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