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Inhibition of T cell-mediated inflammation in uveitis by a novel anti-CD3 antibody

BACKGROUND: A novel anti-mouse CD3ε antibody, Dow2, recognizes mouse CD3ε without activating T cells and suppresses T-cell activation. The purpose of this study was to determine whether Dow2 can inhibit T cells in uveitis. METHODS: Experimental autoimmune uveitis (EAU) was induced in mice by immuniz...

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Detalles Bibliográficos
Autores principales:	Sugita, Sunao, Shimizu, Jun, Makabe, Kenichi, Keino, Hiroshi, Watanabe, Takeshi, Takahashi, Masayo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526238/ https://www.ncbi.nlm.nih.gov/pubmed/28743289 http://dx.doi.org/10.1186/s13075-017-1379-9

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