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Overexpression of serine protease HtrA enhances disruption of adherens junctions, paracellular transmigration and type IV secretion of CagA by Helicobacter pylori

BACKGROUND: The serine protease HtrA is an important factor for regulating stress responses and protein quality control in bacteria. In recent studies, we have demonstrated that the gastric pathogen Helicobacter pylori can secrete HtrA into the extracellular environment, where it cleaves-off the ect...

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Detalles Bibliográficos
Autores principales: Harrer, Aileen, Boehm, Manja, Backert, Steffen, Tegtmeyer, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526239/
https://www.ncbi.nlm.nih.gov/pubmed/28770008
http://dx.doi.org/10.1186/s13099-017-0189-6