Cargando…
Overexpression of serine protease HtrA enhances disruption of adherens junctions, paracellular transmigration and type IV secretion of CagA by Helicobacter pylori
BACKGROUND: The serine protease HtrA is an important factor for regulating stress responses and protein quality control in bacteria. In recent studies, we have demonstrated that the gastric pathogen Helicobacter pylori can secrete HtrA into the extracellular environment, where it cleaves-off the ect...
Autores principales: | Harrer, Aileen, Boehm, Manja, Backert, Steffen, Tegtmeyer, Nicole |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526239/ https://www.ncbi.nlm.nih.gov/pubmed/28770008 http://dx.doi.org/10.1186/s13099-017-0189-6 |
Ejemplares similares
-
Campylobacter jejuni Serine Protease HtrA Induces Paracellular Transmigration of Microbiota across Polarized Intestinal Epithelial Cells
por: Sharafutdinov, Irshad, et al.
Publicado: (2022) -
Rapid paracellular transmigration of Campylobacter jejuni across polarized epithelial cells without affecting TER: role of proteolytic-active HtrA cleaving E-cadherin but not fibronectin
por: Boehm, Manja, et al.
Publicado: (2012) -
Campylobacter jejuni enters gut epithelial cells and impairs intestinal barrier function through cleavage of occludin by serine protease HtrA
por: Harrer, Aileen, et al.
Publicado: (2019) -
Campylobacter jejuni Serine Protease HtrA Cleaves the Tight Junction Component Claudin-8
por: Sharafutdinov, Irshad, et al.
Publicado: (2020) -
Establishment of serine protease htrA mutants in Helicobacter pylori is associated with secA mutations
por: Zawilak-Pawlik, Anna, et al.
Publicado: (2019)