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Genome-wide DNA methylation profile analysis identifies differentially methylated loci associated with ankylosis spondylitis

BACKGROUND: Ankylosing spondylitis (AS) is a chronic rheumatic and autoimmune disease. Little is known about the potential role of DNA methylation in the pathogenesis of AS. This study was undertaken to explore the potential role of DNA methylation in the genetic mechanism of AS. METHODS: In this st...

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Detalles Bibliográficos
Autores principales: Hao, Jiangcan, Liu, Yang, Xu, Jiawen, Wang, Wenyu, Wen, Yan, He, Awen, Fan, Qianrui, Guo, Xiong, Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526246/
https://www.ncbi.nlm.nih.gov/pubmed/28743287
http://dx.doi.org/10.1186/s13075-017-1382-1