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Detection of 22 common leukemic fusion genes using a single-step multiplex qRT-PCR-based assay

BACKGROUND: Fusion genes generated from chromosomal translocation play an important role in hematological malignancies. Detection of fusion genes currently employ use of either conventional RT-PCR methods or fluorescent in situ hybridization (FISH), where both methods involve tedious methodologies a...

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Detalles Bibliográficos
Autores principales: Lyu, Xiaodong, Wang, Xianwei, Zhang, Lina, Chen, Zhenzhu, Zhao, Yu, Hu, Jieying, Fan, Ruihua, Song, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526257/
https://www.ncbi.nlm.nih.gov/pubmed/28743306
http://dx.doi.org/10.1186/s13000-017-0634-3