Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection

BACKGROUND: Epigenetic heterogeneity within a tumour can play an important role in tumour evolution and the emergence of resistance to treatment. It is increasingly recognised that the study of DNA methylation (DNAm) patterns along the genome – so-called ‘epialleles’ – offers greater insight into ep...

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Detalles Bibliográficos
Autores principales: Barrett, James E., Feber, Andrew, Herrero, Javier, Tanic, Miljana, Wilson, Gareth A., Swanton, Charles, Beck, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526259/
https://www.ncbi.nlm.nih.gov/pubmed/28743252
http://dx.doi.org/10.1186/s12859-017-1753-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526259/
https://www.ncbi.nlm.nih.gov/pubmed/28743252
http://dx.doi.org/10.1186/s12859-017-1753-2

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