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Formation of upd(7)mat by trisomic rescue: SNP array typing provides new insights in chromosomal nondisjunction
BACKGROUND: Maternal uniparental disomy (UPD) of chromosome 7 (upd(7)mat) accounts for approximately 10% of patients with Silver-Russell syndrome (SRS). For upd(7)mat and trisomy 7, a significant number of mechanisms have been proposed to explain the postzygotic formation of these chromosomal compos...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526280/ https://www.ncbi.nlm.nih.gov/pubmed/28770003 http://dx.doi.org/10.1186/s13039-017-0329-1 |