Cargando…
R-spondin2, a novel target of NOBOX: identification of variants in a cohort of women with primary ovarian insufficiency
BACKGROUND: R-spondin2 (Rspo2) is a secreted agonist of the canonical Wnt/β-catenin signaling pathway. Rspo2 plays a key role in development of limbs, lungs and hair follicles, and more recently during ovarian follicle development. Rspo2 heterozygous deficient female mice become infertile around 4 m...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526297/ https://www.ncbi.nlm.nih.gov/pubmed/28743298 http://dx.doi.org/10.1186/s13048-017-0345-0 |