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Exosomes derived from gemcitabine-resistant cells transfer malignant phenotypic traits via delivery of miRNA-222-3p

BACKGROUND: Although gemcitabine-based chemotherapy has been established as a core multimodal therapy for non-small cell lung cancer (NSCLC) treatment, its clinical efficacy remains limited by the development of acquired resistance following tumor metastasis and relapse. In this study, we investigat...

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Detalles Bibliográficos
Autores principales: Wei, Feng, Ma, Chengyuan, Zhou, Tong, Dong, Xuechao, Luo, Qinghua, Geng, Li, Ding, Lijuan, Zhang, Yandong, Zhang, Li, Li, Nan, Li, Yang, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526308/
https://www.ncbi.nlm.nih.gov/pubmed/28743280
http://dx.doi.org/10.1186/s12943-017-0694-8