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Farnesoid X Receptor and Liver X Receptor Ligands Initiate Formation of Coated Platelets

OBJECTIVES—: The liver X receptors (LXRs) and farnesoid X receptor (FXR) have been identified in human platelets. Ligands of these receptors have been shown to have nongenomic inhibitory effects on platelet activation by platelet agonists. This, however, seems contradictory with the platelet hyper-r...

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Detalles Bibliográficos
Autores principales: Unsworth, Amanda J., Bye, Alexander P., Tannetta, Dionne S., Desborough, Michael J.R., Kriek, Neline, Sage, Tanya, Allan, Harriet E., Crescente, Marilena, Yaqoob, Parveen, Warner, Timothy D., Jones, Chris I., Gibbins, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526435/
https://www.ncbi.nlm.nih.gov/pubmed/28619996
http://dx.doi.org/10.1161/ATVBAHA.117.309135