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Farnesoid X Receptor and Liver X Receptor Ligands Initiate Formation of Coated Platelets
OBJECTIVES—: The liver X receptors (LXRs) and farnesoid X receptor (FXR) have been identified in human platelets. Ligands of these receptors have been shown to have nongenomic inhibitory effects on platelet activation by platelet agonists. This, however, seems contradictory with the platelet hyper-r...
Autores principales: | Unsworth, Amanda J., Bye, Alexander P., Tannetta, Dionne S., Desborough, Michael J.R., Kriek, Neline, Sage, Tanya, Allan, Harriet E., Crescente, Marilena, Yaqoob, Parveen, Warner, Timothy D., Jones, Chris I., Gibbins, Jonathan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526435/ https://www.ncbi.nlm.nih.gov/pubmed/28619996 http://dx.doi.org/10.1161/ATVBAHA.117.309135 |
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