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Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense

Successful host defense against pathogens requires innate immune recognition of the correct pathogen associated molecular patterns (PAMPs) by pathogen recognition receptors (PRRs) to trigger the appropriate gene program tailored to the pathogen. While many PRR pathways contribute to the innate immun...

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Detalles Bibliográficos
Autores principales: Scumpia, Philip O., Botten, Giovanni A., Norman, Joshua S., Kelly-Scumpia, Kindra M., Spreafico, Roberto, Ruccia, Amber R., Purbey, Prabhat K., Thomas, Brandon J., Modlin, Robert L., Smale, Stephen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526579/
https://www.ncbi.nlm.nih.gov/pubmed/28704551
http://dx.doi.org/10.1371/journal.ppat.1006496