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Wnt/β-catenin promotes gastric fundus specification in mice and humans

Despite the global prevalence of gastric disease, there are few adequate models to study the fundus epithelium of the human stomach. We differentiated human pluripotent stem cells (PSCs) into gastric organoids containing fundic epithelium by first identifying and then recapitulating key events in em...

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Detalles Bibliográficos
Autores principales: McCracken, Kyle W., Zhang, Xinghao, Wells, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526592/
https://www.ncbi.nlm.nih.gov/pubmed/28052057
http://dx.doi.org/10.1038/nature21021