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Wnt/β-catenin promotes gastric fundus specification in mice and humans
Despite the global prevalence of gastric disease, there are few adequate models to study the fundus epithelium of the human stomach. We differentiated human pluripotent stem cells (PSCs) into gastric organoids containing fundic epithelium by first identifying and then recapitulating key events in em...
Autores principales: | McCracken, Kyle W., Zhang, Xinghao, Wells, James M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526592/ https://www.ncbi.nlm.nih.gov/pubmed/28052057 http://dx.doi.org/10.1038/nature21021 |
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