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Simulating clinical trials with and without intracranial EEG data

OBJECTIVE: It is currently unknown whether knowledge of clinically silent (electrographic) seizures improves the statistical efficiency of clinical trials. METHODS: Using data obtained from 10 patients with chronically implanted subdural electrodes over an average of 1 year, a Monte Carlo bootstrapp...

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Detalles Bibliográficos
Autores principales: Goldenholz, Daniel M., Tharayil, Joseph J., Kuzniecky, Rubin, Karoly, Philippa, Theodore, William H., Cook, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526639/
https://www.ncbi.nlm.nih.gov/pubmed/28758158
http://dx.doi.org/10.1002/epi4.12038