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Simulating clinical trials with and without intracranial EEG data
OBJECTIVE: It is currently unknown whether knowledge of clinically silent (electrographic) seizures improves the statistical efficiency of clinical trials. METHODS: Using data obtained from 10 patients with chronically implanted subdural electrodes over an average of 1 year, a Monte Carlo bootstrapp...
Autores principales: | Goldenholz, Daniel M., Tharayil, Joseph J., Kuzniecky, Rubin, Karoly, Philippa, Theodore, William H., Cook, Mark J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526639/ https://www.ncbi.nlm.nih.gov/pubmed/28758158 http://dx.doi.org/10.1002/epi4.12038 |
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