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Altered paracrine signaling from the injured knee joint impairs postnatal long bone growth

Regulation of organ growth is a poorly understood process. In the long bones, the growth plates (GPs) drive elongation by generating a scaffold progressively replaced by bone. Although studies have focused on intrinsic GP regulation, classic and recent experiments suggest that local signals also mod...

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Detalles Bibliográficos
Autores principales: Roselló-Díez, Alberto, Stephen, Daniel, Joyner, Alexandra L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526667/
https://www.ncbi.nlm.nih.gov/pubmed/28741471
http://dx.doi.org/10.7554/eLife.27210